Here are some fascinating studies about dietary selenium and skin cancer prevention:

Plasma Selenium and Skin Neoplasms: A Case‐Control Study (2009)

Conclusion: Study compared the selenium levels of 143 non-melanoma skin cancer patients and 103 healthy controls. The skin cancer patients had “significantly lower” levels of selenium.


Serum Antioxidants and Skin Cancer Risk: An 8-Year Community-Based Follow-up Study (2009)

Conclusion: 485 Australian adults were evaluated for blood levels for antioxidants –  carotenoids, vitamin E, and selenium. They were then divided into three groups – low antioxidant levels, moderate, and high – and monitored for 8 years for development of BCC or SCC skin cancer. A very strong association was found between selenium levels and skin cancer incidence. Those with the highest selenium levels suffered a 60% lower BCC and SCC skin cancer risk compared to those with the lowest selenium levels.


Effects of Dietary Selenium on UVB-Induced Skin Carcinogenesis and Epidermal Antioxidant Status (1994)

Conclusion: Skin tumors were UV-induced in three groups of hairless mice. To test the effect of selenium on skin cancer, the three groups of mice were either given a selenium-deficient diet, a low-selenium diet, or high-selenium diet. After the skin cancer inducement, the mice were no longer subjected to UV irradiation and researchers observed the tumor activity. The mice in the deficient and low-selenium groups continued to suffer tumor activity – the tumors increased. However, the high-selenium group enjoyed an arrest of tumor activity.


Serum Selenium Levels in Patients With Malignant Melanoma (1989)

Conclusion: Study evaluated the selenium levels of 101 melanoma skin cancer patients and found that their selenium were “significantly lower” compared to a healthy control group, with patients in the later stages of melanoma having even lower levels. “Our results, showing for the first time that malignant melanoma is associated with low Se concentrations, are consistent with results of epidemiologic studies showing an inverse correlation between serum Se levels and certain cancers.”


Also see skin cancer studies on 

Vitamin D and Melanoma

Vitamin D and Non-Melanoma Skin Cancer



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